I received a 1000mg bottle for Christmas. I'm a chronic back pain sufferer and usually take pain killers most days, with considerable pain and stiffness in the morning and evening especially. It's 10 days later and I've not had any pain killers. This worked for me by alieviating pain from the first dose. Stiffness is much reduced. I haven't had to be in bed by 9pm as before, just to lie down. I haven't had any of the headaches I usually experience from tension. Walking the dogs I find myself walking with more confidence and faster. No side nor I'll effects to date. This is all hugely positive and suprising for me and is making a much needed and wished for difference to my day to day life. I am looking forward to what I might be able to achieve if this carries on, not least to be able to do my prescribed stretches without tears. Genuinely life changing in my case. I hope it helps you too.