I've only been using Phyla for about two weeks but I have noticed that many deeply clogged pores (blackheads) have surfaced and allowed for a much easier removal. Also, new acne is surfacing and clearing quicker than normal. I really love the serum, I just wish the bottle was bigger and the directions allowed for use of two pumps since one doesn't seem to cover my entire face adequately. I'm plan to continue using!