These drops have stopped our 13yr old Burmese cat from wetting in our bed at night when she sleeps with us. She recently has undergone a bacterial bladder problem and has the start of chronic kidney disease and although we have managed both of those she was wetting at night. We started on these 5 drops twice a day in food and then gradually reducing drops to zero. She stopped wetting completely but when we stopped the drops she had one episode again, so we have continued with 3-4 drops per day and she is stable again. This has been a game changer so thanks so much for a wonderful product.