Being 72 years old initially I started with a low dose, 1 pill after each meal, to see how it affected me. No affect. After one week went to two after each meal. Combined with my insulin it appears to be helping, even when I cheat. I regularly ran 10-12 after a meal and now i’m Down to single digits but best is first thing in the morning. This morning I was 4.6. It does appear to be working for this sceptic. I am planning to order my next bottle. I was taking victoza but feeling sick to your stomach was not for this old man. I’m quite happy taking curalin with zero side effects. If you try Curalin I wish you the best.