All three of my children have been colicky, but with my third child, it was an impossible situation since he wanted to be held all day and the other kids needed my attention. He also has reflux. So between abdominal discomfort and reflux, he needed constant comfort. Evivo helped the discomfort and the reflux, helped him sleep better and made him generally happier. I felt like I could take better care of myself and my family. One criticism is that the packets are packed super tightly so when opened some inevitably spills, but I’m sure this issue could be fixed easily with the manufacturer. I do highly recommend this product and I take comfort that it has been studied. Word of caution: it must be refrigerated or frozen as it does contain live cultures.