We haven’t noticed any changes yet so maybe it takes awhile? I was hoping to reduce gas and hiccups. I did notice though that baby only poops ever couple of days but when he goes, he really goes. Not sure if the probiotic is having a positive effect but going to give it more time. It’s a little hassle to remember to express some milk for mixing but we’re starting to get a routine and baby doesn’t love taking it from the syringe but he’s getting used to it.