If our 5 week old wasn't sleeping or eating, she was crying. She spit up alot, always had a poopy diaper and grunted all night long. The third day of Evivo she showed improvement. The 6th day she was gassy but when looking into probiotics in general (for adults or children) there is a phase of this and it passes. We're 2 weeks in and she's so much better. Went from crying 6hours a day to not even an hour some days! Help tremendously with her diaper rash also.