I was skeptical at first after using other creams and lotions that did nothing but moisturize or exfoliate very slowly; but ten minutes after using Plexaderm for the first time I was amazed! So easy to apply and use. Makes the start of my day beautiful. And although the effects aren't permanent; Plexaderm really does help to train your facial muscles (that make wrinkles) relax and also makes yourself conscious of what muscles you are scrunching when you grimace or frown so you can be more aware of how to relax into a more vibrant face. I love Plexaderm! Thankyou.