Ok so I've been using Agency since September, they are wonderful products! The personalized bottle with Tretinoin 0.009% is a bit strong for me i think it is the peeling that drives me crazy but as far as the other products such as the moisturizer and cleanser I love them and I just switched up to the spot corrector and the SPF. My Doc is great she explains the plans and what she changes up yes it takes a couple of days but they do contact you when it is needed. I will stick with it as long as I am able!