After month 3 of medication I haven't seen any weight loss. I'm sure a lot of it depends on your body and activity level as well. I'm pretty active with my job and do go to the gym occasionally. I also play hockey weekly. I have noticed a reduction in appetite sometimes medication leaves you feeling not so much nauseous but turned off from food. The application of medication is pretty simple and easy to inject, almost pain free. the needles are very small. Customer service is slow to respond. But do eventually get back to you. when inquiring about this medication and program I was told that the price will go no higher than $199 but I noticed the higher dosages go up to 229. So I received a little bit of misinformation there. I may explore other options to look for a better price and maybe better results. As far as signing up and paying for the medication it's pretty hassle free but there are so many options out there nowadays.