I’ve been taking Nad+ for 6 months and I can tell you it’s all been positive. The immediate change I noticed was better sleep followed with extended energy during the day. No more 3pm crash. I experienced better workouts along with subtle changes in my body since NAD+ helped with inflammation. The most incredible change was in my skin at about the third month. I could not believe how bright and lighter my skin was. Just as it was when I was younger. My over all health has improved and I look forward to additional benefits as I continue taking Nad +.