I have struggled for years trying different hand creams, trying to find a cream that would soothe my extremely dry, cracked, painful and quite often bleeding hands. After starting to use Nursem skin fix and hand cream, my hands were feeling softer and less painful after just 2 days. After 10 days, the difference is amazing. I highly recommend Nursem products and will definitely be continuing to use them myself, I just wish I had found Nursem much sooner.